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Anatoly A Starkov Selected Research

Ketoglutarate Dehydrogenase Complex (Oxoglutarate Dehydrogenase)

1/2018Benfotiamine treatment activates the Nrf2/ARE pathway and is neuroprotective in a transgenic mouse model of tauopathy.
7/2013An update on the role of mitochondrial α-ketoglutarate dehydrogenase in oxidative stress.
11/2009Mice deficient in dihydrolipoyl succinyl transferase show increased vulnerability to mitochondrial toxins.
3/2004Mice deficient in dihydrolipoamide dehydrogenase show increased vulnerability to MPTP, malonate and 3-nitropropionic acid neurotoxicity.

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Anatoly A Starkov Research Topics

Disease

10Neurodegenerative Diseases (Neurodegenerative Disease)
11/2020 - 10/2002
6Alzheimer Disease (Alzheimer's Disease)
12/2019 - 03/2004
5Hypoxia (Hypoxemia)
10/2021 - 02/2010
5Brain Injuries (Brain Injury)
06/2018 - 09/2004
4Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
04/2014 - 03/2006
3Tauopathies
01/2018 - 12/2012
3Parkinson Disease (Parkinson's Disease)
01/2016 - 03/2004
3Huntington Disease (Huntington's Disease)
04/2014 - 03/2004
2Infarction (Infarctions)
01/2019 - 02/2012
2Mitochondrial Diseases (Mitochondrial Disease)
01/2019 - 08/2013
2Inflammation (Inflammations)
07/2014 - 12/2012
2Adrenoleukodystrophy (Adrenoleukodystrophy, X-Linked)
08/2013 - 10/2011
2Hyperoxia
02/2012 - 02/2012
2Ischemia
02/2012 - 02/2010
1Lung Neoplasms (Lung Cancer)
06/2020
1Brain Ischemia (Cerebral Ischemia)
01/2019
1Reperfusion Injury
01/2019
1Thiamine Deficiency
01/2018
1Fatty Liver
03/2017
1Melanoma (Melanoma, Malignant)
02/2017
1Multiple Sclerosis
01/2016
1Stroke (Strokes)
01/2015
1Memory Disorders (Memory Loss)
04/2014
1Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar)
12/2012
1Metabolic Diseases (Metabolic Disease)
12/2012
1Cerebral Infarction
02/2012
1Complement Component 6 Deficiency
02/2010
1Traumatic Brain Injuries (Traumatic Brain Injury)
10/2002

Drug/Important Bio-Agent (IBA)

5EnzymesIBA
10/2021 - 03/2004
4AntioxidantsIBA
10/2021 - 10/2011
4Ketoglutarate Dehydrogenase Complex (Oxoglutarate Dehydrogenase)IBA
01/2018 - 03/2004
3Oxygen (Dioxygen)IBA
10/2021 - 02/2012
3CalciumIBA
06/2018 - 09/2004
2Transcription Factors (Transcription Factor)IBA
10/2021 - 12/2012
2LipidsIBA
03/2017 - 12/2012
21- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
01/2016 - 02/2012
2Pharmaceutical PreparationsIBA
01/2015 - 08/2013
2Neuroprotective AgentsIBA
07/2014 - 12/2012
2Proteins (Proteins, Gene)FDA Link
07/2014 - 10/2011
2Peroxisome Proliferator-Activated Receptors (PPAR)IBA
12/2012 - 01/2011
2Superoxide Dismutase-1IBA
11/2011 - 03/2006
2Reactive Oxygen Species (Oxygen Radicals)IBA
09/2003 - 10/2002
1PeroxidesIBA
10/2021
1Oxidants (Oxidizing Agents)IBA
10/2021
1Mitochondrial DNA (mtDNA)IBA
06/2020
1Bexarotene (LGD1069)FDA Link
12/2019
1Presenilin-1IBA
12/2019
1ProdrugsIBA
01/2019
14,6-dinitro-o-cresol (DNOC)IBA
01/2019
1Flavin Mononucleotide (FMN)IBA
01/2019
1Methylene Blue (Methylthioninium Chloride)FDA Link
01/2019
1ubiquinolIBA
01/2019
1Riboflavin (Vitamin B2)FDA LinkGeneric
01/2019
1Electron Transport Complex III (Coenzyme Q-Cytochrome-c Reductase)IBA
01/2019
1Mitochondrial Permeability Transition PoreIBA
06/2018
1TransketolaseIBA
01/2018
1benphothiamine (benfotiamine)IBA
01/2018
1Oxidoreductases (Dehydrogenase)IBA
01/2018
1Glucose (Dextrose)FDA LinkGeneric
01/2018
1Phosphates (Orthophosphate)IBA
01/2018
1Pyruvic Acid (Pyruvate)IBA
01/2018
1Amyloid beta-PeptidesIBA
01/2018
1Thiamine (Aneurin)FDA Link
01/2018
1EstersIBA
01/2018
1AcidsIBA
03/2017
1Citric Acid (Citrate)FDA LinkGeneric
02/2017
1Dimethyl FumarateIBA
01/2016
1citraconic acid (mesaconic acid)IBA
01/2016
1BenzimidazolesIBA
01/2015
1LuciferasesIBA
01/2015
1Deferoxamine (Desferal)FDA LinkGeneric
01/2015
1tau Proteins (tau Protein)IBA
07/2014
1NF-E2-Related Factor 2IBA
07/2014
1Amyloid (Amyloid Fibrils)IBA
04/2014
1Messenger RNA (mRNA)IBA
04/2014
1Pioglitazone (Actos)FDA Link
08/2013
1Fatty Acids (Saturated Fatty Acids)IBA
08/2013
1Member 1 Subfamily D ATP Binding Cassette TransporterIBA
08/2013
1BezafibrateIBA
12/2012
1LigandsIBA
12/2012
1Cyclophilins (Cyclophilin)IBA
09/2012
1Superoxide DismutaseIBA
09/2012
1CatalaseIBA
02/2012
1RotenoneIBA
02/2012
1Free RadicalsIBA
02/2012
1pyridabenIBA
02/2012
1Pyruvate KinaseIBA
10/2011
1Complement Membrane Attack Complex (Membrane Attack Complex)IBA
02/2010
1Complement System Proteins (Complement)IBA
02/2010
1Pyruvate Dehydrogenase Complex (Dehydrogenase Complex, Pyruvate)IBA
03/2004
1Apoptosis Regulatory ProteinsIBA
10/2002

Therapy/Procedure

1Therapeutics
11/2020